Interactor 1: TBP (P20226)
TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
Gene: TBP

Interactor 2: TAF5 (Q15542)
Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100)
Gene: TAF5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.760

The method score is based on:

Property Details
Experiments 9045704, 9153318, 7680771, 35271311, 19240132, 17967894, 17375202, 8858156, 9603525, 9311784, 22323595, 15870280, 9674425, 7744009, 17884155, 10373431
Identification Methods affinity chromatography technology, biochemical, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005669 - transcription factor TFIID complex
GO:0006352 - DNA-templated transcription initiation
and 5 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 339
Hs

1 800
+ Mm
+ Hs
+ Hs
+ Sc
+ Hs
+ Dm
+ Sp
+ Sp

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Last updated: 15 Jul 2024