HitPredict

Interactor 1: TBP (P20226)
TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
Gene: TBP

Interactor 2: TAF7 (Q15545)
Transcription initiation factor TFIID subunit 7 (RNA polymerase II TBP-associated factor subunit F) (Transcription initiation factor TFIID 55 kDa subunit) (TAF(II)55) (TAFII-55) (TAFII55)
Gene: TAF7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.747

The method score is based on:

Property	Details
Experiments	29111974, 12665565, 9153318, 35271311, 19240132, 9603525, 9311784, 22323595, 17158164
Identification Methods	affinity chromatography technology, biochemical, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000976 - transcription cis-regulatory region binding GO:0001673 - male germ cell nucleus GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005669 - transcription factor TFIID complex and 9 others more... GO:0005737 - cytoplasm GO:0006352 - DNA-templated transcription initiation GO:0006366 - transcription by RNA polymerase II GO:0006367 - transcription initiation at RNA polymerase II promoter GO:0016251 - RNA polymerase II general transcription initiation factor activity GO:0042789 - mRNA transcription by RNA polymerase II GO:0051123 - RNA polymerase II preinitiation complex assembly GO:0060261 - positive regulation of transcription initiation by RNA polymerase II GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	339
Hs

1	349

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024