HitPredict

Interactor 1: TBP (P20226)
TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
Gene: TBP

Interactor 2: TAF2 (Q6P1X5)
Transcription initiation factor TFIID subunit 2 (150 kDa cofactor of initiator function) (RNA polymerase II TBP-associated factor subunit B) (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150)
Gene: TAF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

The method score is based on:

Property	Details
Experiments	7680771, 19240132, 17967894, 10373431
Identification Methods	biochemical, pull down, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	association, direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000976 - transcription cis-regulatory region binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005669 - transcription factor TFIID complex GO:0006367 - transcription initiation at RNA polymerase II promoter and 4 others more... GO:0016251 - RNA polymerase II general transcription initiation factor activity GO:0042789 - mRNA transcription by RNA polymerase II GO:0051123 - RNA polymerase II preinitiation complex assembly GO:0060261 - positive regulation of transcription initiation by RNA polymerase II
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	339
Hs

1	1199

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024