HitPredict

Interactor 1: TBP (P20226)
TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
Gene: TBP

Interactor 2: TAF1L (Q8IZX4)
Transcription initiation factor TFIID subunit 1-like (TAF(II)210) (TBP-associated factor 1-like) (TBP-associated factor 210 kDa) (Transcription initiation factor TFIID 210 kDa subunit)
Gene: TAF1L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.775

The method score is based on:

Property Details
Experiments 12217962, 35271311
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DUF3591~TBP, TBP~TBP-binding
Common GO terms GO:0001091 - RNA polymerase II general transcription initiation factor binding
GO:0005654 - nucleoplasm
GO:0005669 - transcription factor TFIID complex
GO:0016251 - RNA polymerase II general transcription initiation factor activity
GO:0051123 - RNA polymerase II preinitiation complex assembly
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 339
Hs

1 1826
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024