HitPredict

Interactor 1: TBP (P20226)
TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
Gene: TBP

Interactor 2: TF2AY (Q9UNN4)
TFIIA-alpha and beta-like factor (General transcription factor II A, 1-like factor)
Gene: GTF2A1L

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12107178
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	TBP~TFIIA
Common GO terms	GO:0001673 - male germ cell nucleus GO:0005672 - transcription factor TFIIA complex GO:0005737 - cytoplasm GO:0006366 - transcription by RNA polymerase II GO:0006367 - transcription initiation at RNA polymerase II promoter
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 478
+	Mm
		913387 TBPL1_MOUSE (155-338): 4.89e-77: 235: 40.22		TF2AY_MOUSE (1-478): 0: 690: 71.34
+	Hs
		589812 TBP_HUMAN (1-339): 7.86e-144: 411: 100.00		TF2AA_HUMAN (2-56): 3.01e-21: 97.2: 60.00
+	Mm
		661515 TBP_MOUSE (1-339): 8.88e-142: 405: 91.15		TF2AA_MOUSE (2-56): 1.45e-21: 98: 60.00
+	Hs
		855409 TBPL2_HUMAN (1-337): 2.72e-140: 402: 59.36		TF2AA_HUMAN (2-56): 3.01e-21: 97.2: 60.00
+	Sc
		526976 TBP_YEAST (120-337): 9.51e-102: 301: 69.73		TOA1_YEAST (326-478): 3.26e-36: 137: 24.84
+	Dm
		589959 TBP_DROME (11-339): 2.81e-105: 314: 54.37		TF2AA_DROME (3-54): 1.12e-18: 89.2: 53.85
+	Ce
		70249 TBPL1_CAEEL (75-336): 9.86e-91: 282: 28.10		O44625_CAEEL (158-478): 8.8e-24: 104: 19.15
+	Dm
		855372 Q8T052_DROME (128-338): 2.89e-78: 253: 37.56		TF2AA_DROME (3-54): 1.12e-18: 89.2: 53.85
+	Mm
		913388 TBPL1_MOUSE (155-338): 4.89e-77: 235: 40.22		TF2AA_MOUSE (2-56): 1.45e-21: 98: 60.00
+	Hs
		855396 TBPL1_HUMAN (155-338): 4.89e-77: 235: 40.22		TF2AA_HUMAN (2-56): 3.01e-21: 97.2: 60.00