HitPredict

Interactor 1: TRYB2 (P20231)
Tryptase beta-2 (Tryptase-2) (EC 3.4.21.59) (Tryptase II)
Gene: TPSB2

Interactor 2: TBB8 (Q3ZCM7)
Tubulin beta-8 chain (Tubulin beta 8 class VIII)
Gene: TUBB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 275 Hs			1 444
+	Hs
		428014 TRYB2_HUMAN (13-275): 6.89e-124: 355: 100.00		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		589991 TRYB2_HUMAN (13-275): 6.89e-124: 355: 100.00		TBB4B_HUMAN (1-427): 0: 719: 91.10
+	Hs
		589992 TRYB2_HUMAN (13-275): 6.89e-124: 355: 100.00		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		589997 TRYB2_HUMAN (13-275): 6.89e-124: 355: 100.00		TBB2B_HUMAN (1-430): 0: 719: 90.23
+	Hs
		381121 TRYB2_HUMAN (13-275): 6.89e-124: 355: 100.00		TBB4A_HUMAN (1-427): 0: 715: 90.16
+	Hs
		589993 TRYB2_HUMAN (13-275): 6.89e-124: 355: 100.00		TBB2A_HUMAN (1-430): 0: 715: 90.00
+	Hs
		381216 PRSS8_HUMAN (4-271): 1.61e-103: 306: 39.56		TBB4A_HUMAN (1-427): 0: 715: 90.16
+	Hs
		428427 TMPS5_HUMAN (19-273): 7.5e-97: 293: 38.08		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		1037390 TMPS5_HUMAN (19-273): 7.5e-97: 293: 38.08		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		933971 TMPS5_HUMAN (19-273): 7.5e-97: 293: 38.08		TBB4B_HUMAN (1-427): 0: 719: 91.10
+	Hs
		428722 TRY2_HUMAN (30-274): 4.3e-99: 291: 34.40		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		1046575 TMPS5_HUMAN (19-273): 7.5e-97: 293: 38.08		TBB2A_HUMAN (1-430): 0: 715: 90.00
+	Hs
		1312808 TMPS5_HUMAN (19-273): 7.5e-97: 293: 38.08		TBB6_HUMAN (1-432): 0: 715: 86.81
+	Hs
		381298 TMPS5_HUMAN (19-273): 7.5e-97: 293: 38.08		TBB4A_HUMAN (1-427): 0: 715: 90.16
+	Hs
		1114233 TMPS5_HUMAN (19-273): 7.5e-97: 293: 38.08		TBB8_HUMAN (1-427): 0: 708: 100.00