HitPredict

Interactor 1: TRYB2 (P20231)
Tryptase beta-2 (Tryptase-2) (EC 3.4.21.59) (Tryptase II)
Gene: TPSB2

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 275 Hs			1 449
+	Hs
		589995 TRYB2_HUMAN (13-275): 6.89e-124: 355: 100.00		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		428014 TRYB2_HUMAN (13-275): 6.89e-124: 355: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		589991 TRYB2_HUMAN (13-275): 6.89e-124: 355: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		589997 TRYB2_HUMAN (13-275): 6.89e-124: 355: 100.00		TBB2B_HUMAN (1-440): 0: 697: 40.23
+	Hs
		1309494 TMPS5_HUMAN (19-273): 7.5e-97: 293: 38.08		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Hs
		933221 PRSS8_HUMAN (4-271): 1.61e-103: 306: 39.56		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		933614 TMPS5_HUMAN (19-273): 7.5e-97: 293: 38.08		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		1175163 BSSP4_HUMAN (3-272): 4.41e-99: 294: 38.85		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		1175177 TMPS5_HUMAN (19-273): 7.5e-97: 293: 38.08		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		714751 TRY3_HUMAN (26-274): 5.64e-97: 288: 34.65		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		428427 TMPS5_HUMAN (19-273): 7.5e-97: 293: 38.08		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		933971 TMPS5_HUMAN (19-273): 7.5e-97: 293: 38.08		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		933689 ST14_HUMAN (31-267): 2.18e-43: 159: 39.11		TBA4A_HUMAN (1-448): 0: 724: 96.21