HitPredict

Interactor 1: PO5F1 (P20263)
POU domain, class 5, transcription factor 1 (NF-A3) (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3)
Gene: Pou5f1

Interactor 2: HELLS (Q60848)
Lymphocyte-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein)
Gene: HELLS

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	20362541, 20362542, 22083510
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:1990830 - cellular response to leukemia inhibitory factor
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 352 Mm			1 821
+	Mm
		56898 PO5F1_MOUSE (1-352): 1.21e-98: 297: 100.00		CHD5_MOUSE (34-818): 0: 597: 24.34
+	Mm
		69793 PO5F1_MOUSE (1-352): 1.21e-98: 297: 100.00		B1AR17_MOUSE (34-811): 0: 596: 23.51
+	Mm
		590316 PO5F1_MOUSE (1-352): 1.21e-98: 297: 100.00		SMCA4_MOUSE (1-820): 0: 581: 25.37
+	Hs
		967993 PO5F1_HUMAN (1-352): 3.56e-88: 271: 82.50		CHD7_HUMAN (3-805): 0: 605: 25.37
+	Mm
		590383 PO5F1_MOUSE (1-352): 1.21e-98: 297: 100.00		CHD4_MOUSE (34-811): 0: 577: 23.02
+	Mm
		590370 PO5F1_MOUSE (1-352): 1.21e-98: 297: 100.00		SMCA2_MOUSE (1-820): 0: 574: 25.54
+	Hs
		839830 LHX2_HUMAN (202-351): 2.78e-34: 131: 24.53		HELLS_HUMAN (1-821): 0: 716: 91.12
+	Mm
		590474 PO5F1_MOUSE (1-352): 1.21e-98: 297: 100.00		SMCA5_MOUSE (86-817): 4.5e-175: 534: 28.63
+	Hs
		1018535 HMBX1_HUMAN (45-323): 2.7e-39: 145: 17.23		CHD3_HUMAN (34-811): 0: 598: 23.51
+	Hs
		839836 LHX2_HUMAN (202-351): 2.78e-34: 131: 24.53		CHD7_HUMAN (3-805): 0: 605: 25.37
+	Hs
		839721 LHX2_HUMAN (202-351): 2.78e-34: 131: 24.53		SMCA4_HUMAN (1-820): 0: 581: 24.67
+	Hs
		839720 LHX2_HUMAN (202-351): 2.78e-34: 131: 24.53		SMCA2_HUMAN (1-820): 0: 572: 25.54
+	Hs
		658642 LHX2_HUMAN (202-351): 2.78e-34: 131: 24.53		SMCA1_HUMAN (98-812): 0: 557: 30.70
+	Hs
		1018559 ZFHX4_HUMAN (208-280): 3.61e-12: 70: 30.14		CHD3_HUMAN (34-811): 0: 598: 23.51
+	Hs
		1059707 ZFHX4_HUMAN (208-280): 3.61e-12: 70: 30.14		CHD4_HUMAN (34-811): 0: 577: 23.02