Interactor 1: PO3F3 (P20264)
POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1) (Octamer-binding protein 8) (Oct-8) (Octamer-binding transcription factor 8) (OTF-8)
Gene: POU3F3

Interactor 2: PO5F1 (Q01860)
POU domain, class 5, transcription factor 1 (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3)
Gene: POU5F1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Homeodomain~Homeodomain, Homeodomain~Pou, Pou~Pou
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 3 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 500
Hs

1 360
+ Hs
+ Hs
+ Mm
+ Hs
+ Rn
+ Dm
+ Mm
+ Dm
+ Dm
+ Mm
+ Hs
+ Dm
+ Hs
+ Mm
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024