HitPredict

Interactor 1: TNR1B (P20333)
Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII) (TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b) (Etanercept) [Cleaved into: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBP-2) (TBPII)]
Gene: TNFRSF1B

Interactor 2: TNR1B (P20333)
Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII) (TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b) (Etanercept) [Cleaved into: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBP-2) (TBPII)]
Gene: TNFRSF1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.806

The method score is based on:

Property Details
Experiments 10875917, 14743216
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, tandem affinity purification
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains TNFR_c6~TNFR_c6
Common GO terms GO:0002718 - regulation of cytokine production involved in immune response
GO:0002724 - regulation of T cell cytokine production
GO:0002947 - tumor necrosis factor receptor superfamily complex
GO:0003176 - aortic valve development
GO:0003177 - pulmonary valve development
and 30 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 461
Hs

1 461
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Last updated: 15 Jul 2024