HitPredict

Interactor 1: TNR1B (P20333)
Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII) (TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b) (Etanercept) [Cleaved into: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBP-2) (TBPII)]
Gene: TNFRSF1B

Interactor 2: CDC6 (Q99741)
Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6)
Gene: CDC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 461 Hs			1 560
+	Hs
		591323 TNR1B_HUMAN (1-461): 5.19e-141: 413: 100.00		ORC1_HUMAN (4-548): 3.74e-94: 308: 22.62
+	Hs
		584460 TNR1A_HUMAN (32-256): 2.62e-36: 141: 22.36		CDC6_HUMAN (1-560): 1.83e-166: 486: 100.00
+	Hs
		661053 TNR8_HUMAN (59-177): 1.74e-11: 68.1: 25.21		CDC6_HUMAN (1-560): 1.83e-166: 486: 100.00
+	Hs
		121527 TR10A_HUMAN (33-118): 8.31e-09: 59.6: 21.98		CDC6_HUMAN (1-560): 1.83e-166: 486: 100.00
+	Hs
		217760 TNF6B_HUMAN (47-277): 2.64e-44: 158: 29.96		ORC4_HUMAN (143-552): 5.24e-66: 222: 14.49
+	Hs
		217776 TNR5_HUMAN (29-267): 7.76e-40: 146: 26.12		ORC4_HUMAN (143-552): 5.24e-66: 222: 14.49
+	Hs
		639556 TNR5_HUMAN (29-267): 7.76e-40: 146: 26.12		RFC5_HUMAN (162-518): 3.37e-64: 215: 17.04