HitPredict

Interactor 1: RAB3A (P20336)
Ras-related protein Rab-3A
Gene: RAB3A

Interactor 2: GDIB (P50395)
Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2)
Gene: GDI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 220 Hs			1 445
+	Hs
		838625 RAB1A_HUMAN (12-220): 2.68e-90: 265: 44.02		GDIB_HUMAN (1-445): 0: 722: 100.00
+	Hs
		591514 RAB3B_HUMAN (1-220): 2.99e-92: 271: 77.73		GDIA_HUMAN (1-444): 0: 714: 86.49
+	Mm
		838709 RAB1A_MOUSE (12-220): 2.68e-90: 265: 44.02		GDIA_MOUSE (1-444): 0: 717: 87.39
+	Hs
		838683 RAB1B_HUMAN (15-220): 4.83e-88: 259: 43.20		GDIB_HUMAN (1-445): 0: 722: 100.00
+	Hs
		678344 RAB1A_HUMAN (12-220): 2.68e-90: 265: 44.02		GDIA_HUMAN (1-444): 0: 714: 86.49
+	Mm
		838710 RAB3A_MOUSE (1-220): 3.77e-88: 260: 99.09		GDIA_MOUSE (1-444): 0: 717: 87.39
+	Hs
		591453 RAB3A_HUMAN (1-220): 5.84e-88: 260: 100.00		GDIA_HUMAN (1-444): 0: 714: 86.49
+	Hs
		678336 RAB8A_HUMAN (15-218): 1.04e-87: 259: 48.53		GDIA_HUMAN (1-444): 0: 714: 86.49
+	Hs
		678394 RAB1B_HUMAN (15-220): 4.83e-88: 259: 43.20		GDIA_HUMAN (1-444): 0: 714: 86.49
+	Dm
		627447 RAB3_DROME (1-220): 9.14e-94: 275: 76.47		Q9VLB7_DROME (1-440): 0: 662: 67.80
+	Ce
		92107 O01577_CAEEL (18-212): 2.89e-99: 288: 39.49		E9P8A8_CAEEL (343-436): 4.46e-39: 138: 57.45
+	Hs
		591507 RAB3B_HUMAN (1-220): 2.99e-92: 271: 77.73		RAE2_HUMAN (4-47): 5.29e-13: 73.1: 50.00
+	Hs
		622577 RAB1A_HUMAN (12-220): 2.68e-90: 265: 44.02		RAE1_HUMAN (4-72): 4.66e-13: 73.1: 37.68
+	Hs
		642723 RAB1A_HUMAN (12-220): 2.68e-90: 265: 44.02		RAE2_HUMAN (4-47): 5.29e-13: 73.1: 50.00
+	Hs
		591450 RAB3A_HUMAN (1-220): 5.84e-88: 260: 100.00		RAE1_HUMAN (4-72): 4.66e-13: 73.1: 37.68
+	Hs
		591451 RAB3A_HUMAN (1-220): 5.84e-88: 260: 100.00		RAE2_HUMAN (4-47): 5.29e-13: 73.1: 50.00
+	Hs
		622570 RAB8A_HUMAN (15-218): 1.04e-87: 259: 48.53		RAE1_HUMAN (4-72): 4.66e-13: 73.1: 37.68
+	Hs
		622619 RAB1B_HUMAN (15-220): 4.83e-88: 259: 43.20		RAE1_HUMAN (4-72): 4.66e-13: 73.1: 37.68
+	Hs
		642718 RAB8A_HUMAN (15-218): 1.04e-87: 259: 48.53		RAE2_HUMAN (4-47): 5.29e-13: 73.1: 50.00
+	Hs
		642743 RAB1B_HUMAN (15-220): 4.83e-88: 259: 43.20		RAE2_HUMAN (4-47): 5.29e-13: 73.1: 50.00