HitPredict

Interactor 1: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Interactor 2: RAE2 (P26374)
Rab proteins geranylgeranyltransferase component A 2 (Choroideremia-like protein) (Rab escort protein 2) (REP-2)
Gene: CHML

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.895

Property	Details
Experiments	34079125, 33961781, 35271311, 37232246
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 218 Hs			1 656
+	Hs
		642719 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAE2_HUMAN (1-656): 0: 980: 100.00
+	Hs
		642738 RAB8B_HUMAN (6-205): 1.17e-89: 264: 42.00		RAE2_HUMAN (1-656): 0: 980: 100.00
+	Hs
		642723 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAE2_HUMAN (1-656): 0: 980: 100.00
+	Hs
		642721 RAB14_HUMAN (3-217): 2.42e-84: 250: 57.21		RAE2_HUMAN (1-656): 0: 980: 100.00
+	Hs
		622571 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAE1_HUMAN (1-652): 0: 946: 71.98
+	Hs
		622608 RAB8B_HUMAN (6-205): 1.17e-89: 264: 42.00		RAE1_HUMAN (1-652): 0: 946: 71.98
+	Hs
		591739 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RAE1_HUMAN (1-652): 0: 946: 71.98
+	Hs
		622577 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAE1_HUMAN (1-652): 0: 946: 71.98
+	Hs
		622574 RAB14_HUMAN (3-217): 2.42e-84: 250: 57.21		RAE1_HUMAN (1-652): 0: 946: 71.98
+	Hs
		678338 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49
+	Dm
		1197044 Q86BK8_DROME (3-218): 6.99e-93: 273: 56.94		Q9VLB7_DROME (176-547): 7.18e-140: 417: 23.75
+	Hs
		838617 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		GDIB_HUMAN (221-606): 7.43e-140: 417: 21.52
+	Hs
		678381 RAB8B_HUMAN (6-205): 1.17e-89: 264: 42.00		GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49
+	Hs
		591751 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49
+	Hs
		838673 RAB8B_HUMAN (6-205): 1.17e-89: 264: 42.00		GDIB_HUMAN (221-606): 7.43e-140: 417: 21.52
+	Hs
		591772 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		GDIB_HUMAN (221-606): 7.43e-140: 417: 21.52
+	Mm
		838709 RAB1A_MOUSE (3-218): 3.01e-85: 252: 38.43		GDIA_MOUSE (167-599): 1.13e-141: 422: 20.49
+	Hs
		678344 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		GDIA_HUMAN (167-599): 2.93e-141: 421: 20.49
+	Hs
		838625 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		GDIB_HUMAN (221-606): 7.43e-140: 417: 21.52
+	At
		656917 RAE1C_ARATH (9-217): 4.89e-87: 257: 40.00		REP_ARATH (201-615): 1.59e-122: 377: 25.86