HitPredict

Interactor 1: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Interactor 2: RAB25 (P57735)
Ras-related protein Rab-25 (CATX-8)
Gene: RAB25

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37232246
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0015031 - protein transport GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 218 Hs			1 213
+	Hs
		895026 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05
+	Hs
		895264 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB1B_HUMAN (6-210): 4.92e-87: 257: 40.98
+	Hs
		591801 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05
+	Hs
		1273009 RAB8B_HUMAN (6-205): 1.17e-89: 264: 42.00		RAB1B_HUMAN (6-210): 4.92e-87: 257: 40.98
+	Dm
		185685 Q7KY04_DROME (6-216): 7.32e-92: 269: 77.25		O18335_DROME (1-211): 4.17e-85: 252: 57.67
+	Hs
		591800 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37
+	Zm
		73944 B4FAE1_MAIZE (6-217): 7.18e-86: 254: 39.15		B4FAE1_MAIZE (6-211): 2.22e-90: 265: 40.78
+	Mm
		880395 RAB4A_MOUSE (1-218): 5.01e-88: 260: 97.71		RAB1B_MOUSE (6-210): 9.69e-87: 256: 40.98
+	Hs
		918846 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05
+	Hs
		918879 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90
+	Hs
		913992 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37
+	Hs
		918944 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAB1B_HUMAN (6-210): 4.92e-87: 257: 40.98
+	Mm
		919000 RAB1A_MOUSE (3-218): 3.01e-85: 252: 38.43		RAB1B_MOUSE (6-210): 9.69e-87: 256: 40.98
+	Hs
		896681 RAB14_HUMAN (3-217): 2.42e-84: 250: 57.21		RAB1B_HUMAN (6-210): 4.92e-87: 257: 40.98
+	Hs
		884467 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAB25_HUMAN (1-213): 9.21e-86: 254: 100.00
+	Hs
		884463 RAB14_HUMAN (3-217): 2.42e-84: 250: 57.21		RAB25_HUMAN (1-213): 9.21e-86: 254: 100.00
+	Hs
		895020 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB14_HUMAN (8-203): 1.14e-53: 172: 44.39
+	Hs
		591795 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RAB14_HUMAN (8-203): 1.14e-53: 172: 44.39
+	Hs
		896605 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAB14_HUMAN (8-203): 1.14e-53: 172: 44.39