HitPredict

Interactor 1: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Interactor 2: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0015031 - protein transport GO:0016192 - vesicle-mediated transport GO:0031982 - vesicle GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 218 Hs			1 116
+	Dm
		577228 Q7KY04_DROME (6-216): 7.32e-92: 269: 77.25		SYB_DROME (1-115): 4.95e-33: 114: 51.91
+	Hs
		850551 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		261647 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		591780 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		895029 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00
+	Hs
		263211 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180851 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		895094 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		261636 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		180812 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		591860 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		591996 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50
+	Hs
		261649 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		918878 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		926211 RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26		VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00
+	Hs
		896624 RAB14_HUMAN (3-217): 2.42e-84: 250: 57.21		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		180855 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		1079324 RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		1079958 RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50
+	Hs
		87580 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		C9JXZ5_HUMAN (46-99): 8.01e-21: 80.9: 37.04