HitPredict

Interactor 1: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Interactor 2: CD226 (Q15762)
CD226 antigen (DNAX accessory molecule 1) (DNAM-1) (CD antigen CD226)
Gene: CD226

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 218 Hs			1 336
+	Hs
		895030 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		CXAR_HUMAN (1-335): 1.95e-47: 165: 15.56
+	Hs
		591809 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		CXAR_HUMAN (1-335): 1.95e-47: 165: 15.56
+	Hs
		895215 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		NECT2_HUMAN (20-189): 7.01e-39: 146: 17.17
+	Hs
		895337 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		JAM1_HUMAN (1-294): 1.04e-40: 146: 18.18
+	Hs
		913999 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		CXAR_HUMAN (1-335): 1.95e-47: 165: 15.56
+	Hs
		895249 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		JAM3_HUMAN (23-315): 3.13e-37: 137: 17.63
+	Hs
		591963 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		NECT2_HUMAN (20-189): 7.01e-39: 146: 17.17
+	Hs
		507847 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		FGFR1_HUMAN (27-315): 5.03e-38: 145: 11.53
+	Hs
		914381 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		NECT3_HUMAN (8-203): 8.75e-42: 154: 20.10
+	Hs
		484281 RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26		VSIG8_HUMAN (8-273): 1.97e-40: 148: 15.17
+	Hs
		507936 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		FGFR1_HUMAN (27-315): 5.03e-38: 145: 11.53
+	Hs
		507935 RAB14_HUMAN (3-217): 2.42e-84: 250: 57.21		FGFR1_HUMAN (27-315): 5.03e-38: 145: 11.53
+	Hs
		914262 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		NECT2_HUMAN (20-189): 7.01e-39: 146: 17.17
+	Hs
		508023 RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26		FGFR1_HUMAN (27-315): 5.03e-38: 145: 11.53
+	Hs
		914415 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		PD1L1_HUMAN (1-287): 5.43e-40: 143: 18.24
+	Hs
		508124 RAB2B_HUMAN (10-218): 1.65e-82: 246: 51.87		FGFR1_HUMAN (27-315): 5.03e-38: 145: 11.53
+	Mm
		919005 RAB1A_MOUSE (3-218): 3.01e-85: 252: 38.43		PD1L1_MOUSE (1-294): 1.55e-37: 137: 16.89
+	Mm
		1265043 RAB14_MOUSE (3-217): 2.42e-84: 250: 57.21		PD1L1_MOUSE (1-294): 1.55e-37: 137: 16.89
+	Mm
		804674 RB11B_MOUSE (3-217): 2.16e-83: 248: 43.26		PD1L1_MOUSE (1-294): 1.55e-37: 137: 16.89
+	Hs
		591975 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		LRIG1_HUMAN (10-206): 1.11e-09: 61.9: 12.32