HitPredict

Interactor 1: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Interactor 2: RUFY2 (Q8WXA3)
RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related)
Gene: RUFY2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RUN~Ras
Common GO terms	GO:0030100 - regulation of endocytosis
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 218 Hs			1 606
+	Hs
		895236 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RUFY1_HUMAN (2-603): 9.52e-53: 194: 62.46
+	Hs
		591988 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RUFY1_HUMAN (2-603): 9.52e-53: 194: 62.46
+	Dm
		1182873 Q7KY04_DROME (6-216): 7.32e-92: 269: 77.25		Q8IMP0_DROME (3-458): 6.76e-47: 178: 41.28
+	Hs
		896669 RAB14_HUMAN (3-217): 2.42e-84: 250: 57.21		RUFY1_HUMAN (2-603): 9.52e-53: 194: 62.46
+	Hs
		914301 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		RUFY1_HUMAN (2-603): 9.52e-53: 194: 62.46
+	Hs
		895143 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RUFY3_HUMAN (7-421): 4.21e-40: 154: 60.72
+	Hs
		895105 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		GRDN_HUMAN (205-552): 1.6e-37: 151: 23.73
+	Hs
		914103 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		GRDN_HUMAN (205-552): 1.6e-37: 151: 23.73
+	Hs
		591904 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		ZFY16_HUMAN (517-602): 5.68e-23: 106: 29.07
+	Hs
		914405 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		MTMR4_HUMAN (451-597): 8.19e-26: 115: 24.67
+	Hs
		313502 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		ZFYV9_HUMAN (535-602): 5.09e-22: 103: 39.13
+	Hs
		591852 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		EEA1_HUMAN (47-561): 6.28e-20: 96.8: 12.67
+	Hs
		914169 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		ZFY16_HUMAN (517-602): 5.68e-23: 106: 29.07
+	Hs
		313523 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		ZFYV9_HUMAN (535-602): 5.09e-22: 103: 39.13
+	Hs
		895213 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		MY18A_HUMAN (2-263): 2.8e-09: 62.5: 11.19
+	Hs
		914203 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		WDFY3_HUMAN (537-594): 6.43e-11: 67.8: 45.00