HitPredict

Interactor 1: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Interactor 2: RB33B (Q9H082)
Ras-related protein Rab-33B
Gene: RAB33B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0015031 - protein transport GO:0032482 - Rab protein signal transduction
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 218 Hs			1 229
+	Hs
		895026 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB1A_HUMAN (23-229): 3.09e-87: 258: 37.62
+	Hs
		895204 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB2B_HUMAN (30-226): 8.06e-87: 257: 38.69
+	Hs
		895264 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB1B_HUMAN (26-229): 8.1e-86: 254: 38.35
+	Mm
		877189 RAB8B_MOUSE (6-205): 2.66e-90: 265: 42.00		RAB8A_MOUSE (26-226): 2.83e-87: 258: 38.54
+	Mm
		867146 RAB2B_MOUSE (9-218): 1.48e-89: 264: 51.16		RAB2A_MOUSE (29-220): 1.13e-86: 257: 39.18
+	Hs
		895216 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB1C_HUMAN (26-229): 1.02e-82: 246: 37.86
+	Hs
		1273009 RAB8B_HUMAN (6-205): 1.17e-89: 264: 42.00		RAB1B_HUMAN (26-229): 8.1e-86: 254: 38.35
+	Hs
		591801 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RAB1A_HUMAN (23-229): 3.09e-87: 258: 37.62
+	Hs
		591794 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RAB2A_HUMAN (29-220): 1.13e-86: 257: 39.18
+	Hs
		591951 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RAB2B_HUMAN (30-226): 8.06e-87: 257: 38.69
+	Zm
		73944 B4FAE1_MAIZE (6-217): 7.18e-86: 254: 39.15		B4FAE1_MAIZE (26-229): 6.15e-89: 262: 36.72
+	Mm
		880395 RAB4A_MOUSE (1-218): 5.01e-88: 260: 97.71		RAB1B_MOUSE (26-229): 1.17e-85: 254: 38.35
+	Hs
		895217 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB8B_HUMAN (26-226): 3.5e-80: 240: 37.44
+	Hs
		918846 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAB1A_HUMAN (23-229): 3.09e-87: 258: 37.62
+	Hs
		918916 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAB2B_HUMAN (30-226): 8.06e-87: 257: 38.69
+	Mm
		919000 RAB1A_MOUSE (3-218): 3.01e-85: 252: 38.43		RAB1B_MOUSE (26-229): 1.17e-85: 254: 38.35
+	Hs
		894787 RAB8B_HUMAN (6-205): 1.17e-89: 264: 42.00		RAB8A_HUMAN (26-226): 4.97e-80: 240: 37.56
+	Hs
		894715 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAB8A_HUMAN (26-226): 4.97e-80: 240: 37.56