HitPredict

Interactor 1: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Interactor 2: RABE2 (Q9H5N1)
Rab GTPase-binding effector protein 2 (Rabaptin-5beta)
Gene: RABEP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	33961781, 21988832
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Rab5-bind~Ras
Common GO terms	GO:0015031 - protein transport
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 218 Hs			1 569
+	Dm
		1197049 Q86BK8_DROME (3-218): 6.99e-93: 273: 56.94		Q9W2M0_DROME (14-547): 1.35e-62: 219: 18.93
+	Hs
		895123 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		MRCKA_HUMAN (241-552): 1.9e-37: 150: 16.30
+	Hs
		914124 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		MRCKA_HUMAN (241-552): 1.9e-37: 150: 16.30
+	Hs
		591853 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RABE1_HUMAN (21-306): 2.47e-24: 109: 32.40
+	Hs
		918873 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RABE1_HUMAN (21-306): 2.47e-24: 109: 32.40
+	Hs
		914082 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		RABE1_HUMAN (21-306): 2.47e-24: 109: 32.40
+	Hs
		895003 RAB4B_HUMAN (6-218): 4.89e-83: 247: 87.32		RABE1_HUMAN (21-306): 2.47e-24: 109: 32.40
+	Hs
		914383 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		MYO5C_HUMAN (1-429): 2.21e-11: 69.3: 13.67
+	Hs
		148636 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		CTRO_HUMAN (12-552): 8.68e-10: 63.9: 12.79
+	Hs
		149274 RAB1B_HUMAN (6-218): 6.6e-83: 246: 39.44		CTRO_HUMAN (12-552): 8.68e-10: 63.9: 12.79