HitPredict

Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Interactor 2: EFNB1 (P98172)
Ephrin-B1 (EFL-3) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) [Cleaved into: Ephrin-B1 C-terminal fragment (Ephrin-B1 CTF); Ephrin-B1 intracellular domain (Ephrin-B1 ICD)]
Gene: EFNB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0045121 - membrane raft GO:0070062 - extracellular exosome GO:2000785 - regulation of autophagosome assembly
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 346
+	Hs
		844483 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		914008 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		592174 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		844450 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856521 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39