HitPredict

Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Interactor 2: LRP8 (Q14114)
Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2)
Gene: LRP8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0030424 - axon GO:0030425 - dendrite GO:0043025 - neuronal cell body
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 963
+	Hs
		844515 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		LRP8_HUMAN (1-963): 0: 814: 100.00
+	Hs
		914062 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		LRP8_HUMAN (1-963): 0: 814: 100.00
+	Hs
		254254 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		LRP4_HUMAN (379-785): 9.67e-89: 313: 30.73
+	Hs
		592200 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		LRP2_HUMAN (195-464): 3.85e-10: 66.4: 16.03
+	Hs
		351048 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		LDLR_HUMAN (683-895): 4.15e-09: 62.6: 10.65
+	Hs
		844482 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		LRP2_HUMAN (195-464): 3.85e-10: 66.4: 16.03
+	Hs
		914007 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		LRP2_HUMAN (195-464): 3.85e-10: 66.4: 16.03
+	Hs
		914028 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		LRP1_HUMAN (5-257): 6.13e-09: 62.6: 13.53