Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A
Interactor 2: RABE1 (Q15276)
Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17)
Gene: RABEP1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.970 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9045618, 9524117, 26430212, 8521472, 34079125, 11718716, 10720461, 15328530, 15378032 |
| Identification Methods | two hybrid, biochemical, pull down, proximity labelling technology, affinity chromatography technology, x-ray crystallography |
| Interaction Type | direct interaction, association, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Rab5-bind~Ras |
| Common GO terms | GO:0005768 - endosome GO:0005769 - early endosome GO:0006897 - endocytosis GO:0031901 - early endosome membrane GO:0043231 - intracellular membrane-bounded organelle |
| Homologous interactions | 8 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
