HitPredict

Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Interactor 2: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	34079125, 32814053
Identification Methods	proximity labelling technology, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045121 - membrane raft GO:0070062 - extracellular exosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 161
+	Hs
		1152088 RAB1B_HUMAN (13-213): 3.05e-87: 257: 41.79		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		918888 RAB1A_HUMAN (11-213): 2.59e-87: 257: 41.18		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		844572 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		914141 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00