HitPredict

Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Interactor 2: VRK2 (Q86Y07)
Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2)
Gene: VRK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 508
+	Hs
		592109 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		MARK3_HUMAN (22-469): 8.37e-112: 350: 14.22
+	Hs
		592336 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		MARK2_HUMAN (3-485): 1.13e-111: 350: 13.73
+	Hs
		844599 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		VRK2_HUMAN (1-508): 1.87e-117: 357: 100.00
+	Hs
		914187 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		VRK2_HUMAN (1-508): 1.87e-117: 357: 100.00
+	Hs
		844585 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		MARK2_HUMAN (3-485): 1.13e-111: 350: 13.73
+	Hs
		647864 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		MARK3_HUMAN (22-469): 8.37e-112: 350: 14.22
+	Hs
		914159 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		MARK2_HUMAN (3-485): 1.13e-111: 350: 13.73
+	Zm
		8047 B4F7V6_MAIZE (13-214): 3.38e-77: 232: 62.87		A0A1D6EK73_MAIZE (17-443): 2.82e-112: 343: 13.75
+	Hs
		844817 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		KC1G3_HUMAN (24-408): 2.13e-105: 323: 23.65
+	Hs
		914504 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		KC1G3_HUMAN (24-408): 2.13e-105: 323: 23.65
+	Hs
		822235 RAB1A_HUMAN (11-213): 2.59e-87: 257: 41.18		KC1D_HUMAN (21-465): 9.4e-99: 305: 22.37
+	Sc
		350855 YPT1_YEAST (14-213): 5.55e-88: 259: 39.02		HRR25_YEAST (21-350): 4.67e-91: 288: 25.60