Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Interactor 2: PK3C3 (Q8NEB9)
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphatidylinositol 3-kinase p100 subunit) (Phosphoinositide-3-kinase class 3) (hVps34)
Gene: PIK3C3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 34079125, 15016378, 15328530
Identification Methods proximity labelling technology, affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PI3_PI4_kinase~Ras
Common GO terms GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0006897 - endocytosis
GO:0030670 - phagocytic vesicle membrane
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 215
Hs

1 887
+ Dm
+ Sc
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm

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Last updated: 15 Jul 2024