HitPredict

Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Interactor 2: OSB11 (Q9BXB4)
Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11)
Gene: OSBPL11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.817

Property	Details
Experiments	31980649, 34079125, unassigned2173
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005654 - nucleoplasm GO:0005794 - Golgi apparatus GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 747
+	Hs
		844713 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		OSB11_HUMAN (1-747): 0: 707: 100.00
+	Hs
		914325 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		OSB11_HUMAN (1-747): 0: 707: 100.00
+	Hs
		592471 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		OSB10_HUMAN (12-739): 0: 628: 54.85
+	Hs
		914326 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		OSB10_HUMAN (12-739): 0: 628: 54.85
+	Hs
		592450 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		OSBL9_HUMAN (60-738): 0: 559: 35.98
+	Hs
		844697 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		OSBL9_HUMAN (60-738): 0: 559: 35.98
+	Hs
		914300 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		OSBL9_HUMAN (60-738): 0: 559: 35.98
+	Hs
		592475 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		OSBL8_HUMAN (9-747): 1.25e-140: 437: 23.03
+	Hs
		844716 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		OSBL8_HUMAN (9-747): 1.25e-140: 437: 23.03
+	Hs
		914333 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		OSBL8_HUMAN (9-747): 1.25e-140: 437: 23.03
+	Dm
		90638 RAB5_DROME (6-213): 9.84e-98: 284: 75.00		E1JH23_DROME (285-686): 1.36e-121: 371: 39.57
+	Dm
		1358753 RAB5_DROME (6-213): 9.84e-98: 284: 75.00		Q9W0K9_DROME (63-283): 1.11e-30: 122: 33.76