HitPredict

Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Interactor 2: OSBL8 (Q9BZF1)
Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8)
Gene: OSBPL8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 889
+	Hs
		844716 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		OSBL8_HUMAN (1-889): 0: 1210: 100.00
+	Hs
		914333 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		OSBL8_HUMAN (1-889): 0: 1210: 100.00
+	Hs
		592450 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		OSBL9_HUMAN (209-743): 5.35e-159: 484: 30.32
+	Hs
		844697 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		OSBL9_HUMAN (209-743): 5.35e-159: 484: 30.32
+	Hs
		914300 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		OSBL9_HUMAN (209-743): 5.35e-159: 484: 30.32
+	Hs
		592471 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		OSB10_HUMAN (283-749): 1.96e-139: 435: 29.46
+	Hs
		914326 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		OSB10_HUMAN (283-749): 1.96e-139: 435: 29.46
+	Hs
		592470 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		OSB11_HUMAN (345-749): 6.21e-130: 409: 29.62
+	Hs
		844713 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		OSB11_HUMAN (345-749): 6.21e-130: 409: 29.62
+	Hs
		914325 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		OSB11_HUMAN (345-749): 6.21e-130: 409: 29.62
+	Dm
		90638 RAB5_DROME (6-213): 9.84e-98: 284: 75.00		E1JH23_DROME (354-695): 7.38e-116: 361: 32.13