HitPredict

Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Interactor 2: ANFY1 (Q9P2R3)
Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif)
Gene: ANKFY1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.876

The method score is based on:

Property Details
Experiments 24102721, 34079125, 15328530
Identification Methods pull down, affinity chromatography technology, proximity labelling technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Ras, Ank_2~Ras
Common GO terms GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005829 - cytosol
GO:0006897 - endocytosis
GO:0010008 - endosome membrane
and 2 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 215
Hs

1 1169
+ Dm
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024