Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Interactor 2: DP13A (Q9UKG1)
DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)
Gene: APPL1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 16622416, 29568061, 32296183, 34079125, 15016378, 17581628, 18034774, unassigned1304
Identification Methods affinity chromatography technology, proximity labelling technology, two hybrid, pull down, validated two hybrid, surface plasmon resonance, two hybrid prey pooling approach, two hybrid array
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PH~Ras
Common GO terms GO:0001726 - ruffle
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005829 - cytosol
and 5 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 215
Hs

1 709
+ Dr
+ Hs
+ Hs
+ Hs
+ Hs
+ Dr
+ Hs
+ Hs
+ Mm
+ Ce
+ Mm
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024