HitPredict

Interactor 1: GNAI (P20353)
G protein alpha i subunit (Guanine nucleotide-binding protein G(i) subunit alpha 65A)
Gene: Galphai

Interactor 2: RGS (Q9VCX1)
Regulator of G-protein signaling loco (RGS) (Locomotion defects protein) (Loco)
Gene: loco

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.800

The method score is based on:

Property Details
Experiments 15937221, 10079238
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains G-alpha~RGS
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0007419 - ventral cord development
GO:0016324 - apical plasma membrane
and 6 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 355
Dm

1 1541
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024