HitPredict

Interactor 1: MTAP2 (P20357)
Microtubule-associated protein 2 (MAP-2)
Gene: Map2

Interactor 2: SPAST (Q9QYY8)
Spastin (EC 5.6.1.1)
Gene: SPAST

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001578 - microtubule bundle formation GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0007409 - axonogenesis GO:0008017 - microtubule binding and 1 others more... GO:0015630 - microtubule cytoskeleton
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1828 Mm			1 614
+	Rn
		545066 MTAP2_RAT (1-1828): 0: 667: 90.39		KTNA1_RAT (177-611): 8.72e-128: 386: 32.53
+	Hs
		807827 MAP1B_HUMAN (51-1813): 3.81e-100: 361: 9.85		AFG2B_HUMAN (7-614): 3.87e-120: 375: 22.02
+	Mm
		1351631 PCLO_MOUSE (2-1817): 1.39e-39: 164: 9.67		SPAST_MOUSE (1-614): 4.16e-146: 438: 100.00
+	Hs
		497797 TAU_HUMAN (1097-1828): 1.29e-56: 214: 22.57		VPS4A_HUMAN (285-613): 4.9e-113: 346: 37.88
+	Mm
		1208058 ANK2_MOUSE (123-1550): 1.37e-11: 72.5: 13.29		SPAST_MOUSE (1-614): 4.16e-146: 438: 100.00
+	Mm
		498014 TAU_MOUSE (1128-1828): 9.81e-61: 225: 23.37		TERA_MOUSE (1-344): 8.28e-45: 172: 9.46
+	Hs
		496648 TAU_HUMAN (1097-1828): 1.29e-56: 214: 22.57		TERA_HUMAN (1-344): 8.28e-45: 172: 9.46
+	Hs
		265390 TAU_HUMAN (1097-1828): 1.29e-56: 214: 22.57		KTNA1_HUMAN (26-252): 7.23e-19: 91.8: 12.55
+	Hs
		875442 SRRM2_HUMAN (9-1803): 7.23e-30: 132: 8.81		TERA_HUMAN (1-344): 8.28e-45: 172: 9.46
+	Hs
		177533 CIC_HUMAN (19-1792): 1.56e-17: 91.9: 8.63		NVL_HUMAN (16-284): 6.65e-37: 149: 12.76