HitPredict

Interactor 1: SRP54 (P20424)
Signal recognition particle subunit SRP54 (EC 3.6.5.4) (Signal recognition particle 54 kDa protein homolog)
Gene: SRP54

Interactor 2: SRP72 (P38688)
Signal recognition particle subunit SRP72 (Signal recognition particle 72 kDa protein homolog)
Gene: SRP72

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.706

Property	Details
Experiments	11805826, 16429126, 37968396, 10921896, 14681587
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005786 - signal recognition particle, endoplasmic reticulum targeting GO:0006614 - SRP-dependent cotranslational protein targeting to membrane GO:0006617 - SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition GO:0008312 - 7S RNA binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 541 Sc			1 640
+	Hs
		283449 SRP54_HUMAN (1-516): 0: 563: 47.89		SRP72_HUMAN (9-638): 0: 533: 20.87
+	Sc
		701644 SRPR_YEAST (14-303): 1.69e-85: 278: 21.85		SRP72_YEAST (1-629): 0: 628: 100.00
+	Hs
		283361 SRPRA_HUMAN (13-303): 2.19e-95: 305: 22.54		SRP72_HUMAN (9-638): 0: 533: 20.87