HitPredict

Interactor 1: CG12 (P20438)
G1/S-specific cyclin CLN2
Gene: CLN2

Interactor 2: CDC53 (Q12018)
Cell division control protein 53 (Cullin-A) (E3 ubiquitin ligase complex SCF subunit CDC53)
Gene: CDC53

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	8756727, 15200949
Identification Methods	affinity chromatography technology, coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000082 - G1/S transition of mitotic cell cycle GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0051301 - cell division
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 545 Sc			1 815
+	Sc
		593372 CG11_YEAST (6-541): 1.12e-151: 447: 56.12		CDC53_YEAST (1-815): 0: 773: 100.00
+	Sc
		526793 CG13_YEAST (8-422): 1.44e-65: 225: 16.82		CDC53_YEAST (1-815): 0: 773: 100.00
+	Hs
		943787 CCNA1_HUMAN (11-299): 6.55e-70: 233: 15.23		CUL1_HUMAN (7-815): 0: 741: 29.92
+	Hs
		590180 CCNA2_HUMAN (4-302): 3.84e-69: 230: 16.12		CUL1_HUMAN (7-815): 0: 741: 29.92
+	Sc
		624752 CG23_YEAST (16-215): 5.59e-56: 195: 20.40		CDC53_YEAST (1-815): 0: 773: 100.00
+	Dm
		872345 CCNE_DROME (41-420): 4.64e-73: 248: 13.94		CUL1_DROME (2-815): 0: 708: 28.25
+	Hs
		538541 CCNB1_HUMAN (2-322): 2.95e-77: 251: 12.81		CUL3_HUMAN (10-815): 0: 696: 21.12
+	Hs
		624588 CCNE1_HUMAN (42-391): 4.03e-65: 219: 12.13		CUL3_HUMAN (10-815): 0: 696: 21.12
+	Hs
		624589 CCNE1_HUMAN (42-391): 4.03e-65: 219: 12.13		CUL4B_HUMAN (5-815): 0: 695: 21.14
+	Dm
		872347 CCNE_DROME (41-420): 4.64e-73: 248: 13.94		Q5BI50_DROME (5-815): 0: 663: 21.09