HitPredict

Interactor 1: KPCA (P20444)
Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)
Gene: Prkca

Interactor 2: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 27507650, 28671696, 36417873
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Pkinase, Pkinase~SAM_1
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007611 - learning or memory
GO:0008270 - zinc ion binding
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 672
Mm

1 1730
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024