HitPredict

Interactor 1: DBP4 (P20448)
ATP-dependent RNA helicase HCA4 (EC 3.6.4.13) (DEAD box protein 4) (Helicase CA4) (Helicase UF1)
Gene: HCA4

Interactor 2: ESF1 (Q06344)
Pre-rRNA-processing protein ESF1 (18S rRNA factor 1)
Gene: ESF1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.705

Property	Details
Experiments	16554755, 29054886, 37968396, 14690591
Identification Methods	affinity chromatography technology, two hybrid, tandem affinity purification, two hybrid array, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005730 - nucleolus GO:0006364 - rRNA processing GO:0030490 - maturation of SSU-rRNA and 1 others more... GO:0032040 - small-subunit processome
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 770 Sc			1 628
+	Sc
		976864 HAS1_YEAST (3-491): 5.9e-117: 364: 38.34		ESF1_YEAST (1-611): 8.13e-170: 499: 100.00
+	Sc
		753051 RRP3_YEAST (43-407): 3.57e-55: 199: 35.15		ESF1_YEAST (1-611): 8.13e-170: 499: 100.00
+	Hs
		1328084 DDX47_HUMAN (39-405): 2.75e-61: 215: 35.87		ESF1_HUMAN (46-592): 3.77e-100: 326: 29.78