HitPredict

Interactor 1: DBP4 (P20448)
ATP-dependent RNA helicase HCA4 (EC 3.6.4.13) (DEAD box protein 4) (Helicase CA4) (Helicase UF1)
Gene: HCA4

Interactor 2: NOP12 (Q08208)
Nucleolar protein 12
Gene: NOP12

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	11805826, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 770 Sc			1 459
+	Hs
		789439 DDX10_HUMAN (3-764): 1.75e-121: 387: 35.07		RBM34_HUMAN (10-430): 4.45e-68: 225: 26.59
+	Sc
		976875 HAS1_YEAST (3-491): 5.9e-117: 364: 38.34		NOP12_YEAST (1-459): 4.83e-75: 244: 100.00
+	Hs
		789490 DDX54_HUMAN (14-767): 4.85e-116: 373: 21.26		RBM34_HUMAN (10-430): 4.45e-68: 225: 26.59
+	Hs
		1254765 DDX54_HUMAN (14-767): 4.85e-116: 373: 21.26		PABP5_HUMAN (9-359): 5.36e-46: 165: 12.30
+	Hs
		1077436 DDX17_HUMAN (7-450): 2.25e-125: 393: 27.17		ELAV1_HUMAN (154-360): 1.32e-32: 128: 13.85
+	Mm
		857323 DDX17_MOUSE (7-450): 1.92e-124: 388: 27.17		TIA1_MOUSE (273-459): 8.21e-34: 132: 12.23
+	Sc
		865748 HAS1_YEAST (3-491): 5.9e-117: 364: 38.34		NOP13_YEAST (27-400): 8.6e-41: 152: 17.73
+	Mm
		857351 Q8BTS0_MOUSE (7-468): 1.77e-122: 382: 27.16		TIA1_MOUSE (273-459): 8.21e-34: 132: 12.23
+	Hs
		571469 DDX5_HUMAN (7-468): 2.47e-122: 382: 26.94		ELAV1_HUMAN (154-360): 1.32e-32: 128: 13.85
+	Mm
		936480 DDX5_MOUSE (7-468): 2.42e-123: 384: 27.16		TIAR_MOUSE (271-459): 4.76e-28: 116: 13.17
+	Hs
		1073611 DDX17_HUMAN (7-450): 2.25e-125: 393: 27.17		SF3B4_HUMAN (269-458): 2.8e-22: 100: 14.56
+	Hs
		1073596 DDX42_HUMAN (7-749): 2.49e-119: 383: 18.10		SF3B4_HUMAN (269-458): 2.8e-22: 100: 14.56
+	Sc
		699738 DRS1_YEAST (43-418): 9.8e-52: 194: 32.38		NOP12_YEAST (1-459): 4.83e-75: 244: 100.00
+	Hs
		789546 DDX31_HUMAN (64-488): 9.9e-58: 213: 32.60		RBM34_HUMAN (10-430): 4.45e-68: 225: 26.59
+	Sc
		638879 SPB4_YEAST (55-489): 4.52e-52: 193: 31.36		NOP12_YEAST (1-459): 4.83e-75: 244: 100.00
+	Hs
		1063282 DDX47_HUMAN (39-405): 2.75e-61: 215: 35.87		SART3_HUMAN (31-408): 3.53e-46: 173: 14.86
+	Hs
		1063286 DDX31_HUMAN (64-488): 9.9e-58: 213: 32.60		SART3_HUMAN (31-408): 3.53e-46: 173: 14.86
+	Sc
		699709 DRS1_YEAST (43-418): 9.8e-52: 194: 32.38		NOP13_YEAST (27-400): 8.6e-41: 152: 17.73
+	Sc
		638828 SPB4_YEAST (55-489): 4.52e-52: 193: 31.36		NOP13_YEAST (27-400): 8.6e-41: 152: 17.73