Interactor 1: DBP5 (P20449)
ATP-dependent RNA helicase DBP5 (EC 3.6.4.13) (DEAD box protein 5) (Helicase CA5/6) (Ribonucleic acid-trafficking protein 8)
Gene: DBP5

Interactor 2: GLE1 (Q12315)
mRNA export factor GLE1 (Nuclear pore protein GLE1) (Nucleoporin GLE1) (RNA export factor GLE1)
Gene: GLE1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 10610322, 21441902, 19805289, 10523319, 16783364, 28869701, 35286399
Identification Methods affinity chromatography technology, molecular sieving, two hybrid, atpase assay, x-ray crystallography, pull down, enzymatic study, fluorescent resonance energy transfer
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains GLE1~Helicase_C
Common GO terms GO:0005737 - cytoplasm
GO:0006406 - mRNA export from nucleus
GO:0006409 - tRNA export from nucleus
GO:0015031 - protein transport
GO:0016973 - poly(A)+ mRNA export from nucleus
and 2 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 482
Sc

1 538
+ Hs
+ At
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024