Interactor 1: PP2BB (P16298)
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calmodulin-dependent calcineurin A subunit beta isoform) (CNA beta)
Gene: PPP3CB

Interactor 2: RUNX1 (Q01196)
Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit)
Gene: RUNX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.55 0.518

The method score is based on:

Property Details
Experiments 35914814
Identification Methods two hybrid, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005509 - calcium ion binding
GO:0005654 - nucleoplasm
GO:0045893 - positive regulation of DNA-templated transcription
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 0

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Last updated: 11Aug2025