HitPredict

Interactor 1: MSH3 (P20585)
DNA mismatch repair protein Msh3 (hMSH3) (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1)
Gene: MSH3

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	31495888, 37071664, 37059091, 19596235
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0006281 - DNA repair
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1137 Hs			1 1834
+	Hs
		855506 MSH6_HUMAN (81-1126): 0: 978: 22.85		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		794278 MSH2_HUMAN (239-1127): 0: 777: 23.81		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		855521 MSH6_HUMAN (81-1126): 0: 978: 22.85		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57
+	Hs
		794289 MSH2_HUMAN (239-1127): 0: 777: 23.81		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57