HitPredict

Interactor 1: MX1 (P20591)
Interferon-induced GTP-binding protein Mx1 (Interferon-induced protein p78) (IFI-78K) (Interferon-regulated resistance GTP-binding protein MxA) (Myxoma resistance protein 1) (Myxovirus resistance protein 1) [Cleaved into: Interferon-induced GTP-binding protein Mx1, N-terminally processed]
Gene: MX1

Interactor 2: MX1 (P20591)
Interferon-induced GTP-binding protein Mx1 (Interferon-induced protein p78) (IFI-78K) (Interferon-regulated resistance GTP-binding protein MxA) (Myxoma resistance protein 1) (Myxovirus resistance protein 1) [Cleaved into: Interferon-induced GTP-binding protein Mx1, N-terminally processed]
Gene: MX1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.961

The method score is based on:

Property Details
Experiments 25416956, 25447205, 32296183, 20428112, 25295396, unassigned1304
Identification Methods two hybrid, biochemical, x-ray crystallography, anti tag coimmunoprecipitation, cosedimentation in solution, two hybrid array, molecular sieving, static light scattering, gtpase assay, two hybrid prey pooling approach and 1 others

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Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Dynamin_M~Dynamin_M, Dynamin_M~Dynamin_N, Dynamin_M~GED, Dynamin_N~Dynamin_N, GED~GED
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
and 16 others

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Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 662
Hs

1 662
+ At
+ Hs
+ Mm
+ Hs
+ Rn
+ Sc
+ At
+ At
+ At
+ At
+ At
+ Hs
+ Hs
+ Dm
+ Sc
+ At
+ At

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Last updated: 15 Jul 2024