Interactor 1: ANPRB (P20594)
Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B)
Gene: NPR2

Interactor 2: ANFC (P23582)
C-type natriuretic peptide [Cleaved into: CNP-22; CNP-29; CNP-53]
Gene: NPPC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.845

The method score is based on:

Property Details
Experiments 1309330, 1660465, 1672777
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANP
Common GO terms GO:0001549 - cumulus cell differentiation
GO:0001974 - blood vessel remodeling
GO:0006182 - cGMP biosynthetic process
GO:0007168 - receptor guanylyl cyclase signaling pathway
GO:0035483 - gastric emptying
and 5 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1047
Hs

1 126
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024