HitPredict

Interactor 1: PP11 (P20604)
Serine/threonine-protein phosphatase PP1-1 (EC 3.1.3.16)
Gene: SIT4

Interactor 2: HRR25 (P29295)
Casein kinase I homolog HRR25 (EC 2.7.11.1)
Gene: HRR25

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	11805837, 23864707
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002098 - tRNA wobble uridine modification GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006281 - DNA repair
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 311 Sc			1 494
+	Hs
		915182 PP2AB_HUMAN (2-311): 0: 520: 57.10		KCC2B_HUMAN (4-490): 1.43e-123: 377: 13.80
+	Hs
		930835 PP2AA_HUMAN (1-311): 0: 519: 56.59		KCC2B_HUMAN (4-490): 1.43e-123: 377: 13.80
+	Hs
		647866 PP2AB_HUMAN (2-311): 0: 520: 57.10		MARK3_HUMAN (6-491): 1.87e-119: 369: 14.84
+	Hs
		830321 PP1A_HUMAN (6-305): 0: 506: 42.86		KC1E_HUMAN (1-398): 1.33e-127: 379: 51.47
+	Hs
		821981 PP2AA_HUMAN (1-311): 0: 519: 56.59		KC1A_HUMAN (2-327): 1.94e-123: 365: 58.28
+	Hs
		737653 PP1G_HUMAN (11-301): 0: 503: 43.73		KC1E_HUMAN (1-398): 1.33e-127: 379: 51.47
+	Hs
		931045 PP2AA_HUMAN (1-311): 0: 519: 56.59		AKT3_HUMAN (3-359): 2.4e-120: 362: 13.46
+	Hs
		682162 PP2AA_HUMAN (1-311): 0: 519: 56.59		AKT2_HUMAN (4-354): 7.05e-120: 361: 14.53
+	Hs
		915183 PP2AB_HUMAN (2-311): 0: 520: 57.10		KCC2G_HUMAN (4-450): 3.13e-118: 360: 15.08
+	Hs
		930836 PP2AA_HUMAN (1-311): 0: 519: 56.59		KCC2G_HUMAN (4-450): 3.13e-118: 360: 15.08
+	Hs
		737650 PP1G_HUMAN (11-301): 0: 503: 43.73		KC1A_HUMAN (2-327): 1.94e-123: 365: 58.28
+	Hs
		135398 PPP6_HUMAN (7-292): 3.77e-148: 419: 65.39		KC1D_HUMAN (1-412): 9e-131: 387: 50.12