HitPredict

Interactor 1: PSB1 (P20618)
Proteasome subunit beta type-1 (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain)
Gene: PSMB1

Interactor 2: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11205743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 241 Hs			1 603
+	Hs
		831961 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		156257 PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		861682 PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		638091 PSA4_HUMAN (8-240): 1.49e-75: 231: 17.72		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		656180 PSA5_HUMAN (16-240): 7.6e-75: 228: 16.67		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		656685 PSB5_HUMAN (9-230): 4.76e-73: 224: 20.27		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		656573 PSB6_HUMAN (34-236): 8.15e-56: 180: 21.68		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Ce
		711591 PSB3_CAEEL (31-241): 9.79e-79: 237: 25.94		PLK1_CAEEL (22-599): 0: 536: 50.58
+	Ce
		711253 PSB1_CAEEL (6-241): 3.46e-76: 232: 39.83		PLK1_CAEEL (22-599): 0: 536: 50.58
+	Ce
		711725 PSA4_CAEEL (7-241): 2.33e-75: 230: 17.36		PLK1_CAEEL (22-599): 0: 536: 50.58
+	Ce
		711668 PSA7_CAEEL (17-240): 1.78e-74: 228: 16.38		PLK1_CAEEL (22-599): 0: 536: 50.58
+	Ce
		711692 Q966I8_CAEEL (34-237): 9.62e-63: 197: 26.47		PLK1_CAEEL (22-599): 0: 536: 50.58
+	Zm
		8048 B4FRQ7_MAIZE (33-241): 2.37e-83: 249: 49.77		A0A1D6EK73_MAIZE (37-348): 4.21e-137: 410: 33.55
+	Zm
		43396 A0A1D6PJW1_MAIZE (16-226): 2.19e-77: 237: 18.35		A0A1D6QH07_MAIZE (47-400): 2.85e-139: 414: 28.05
+	Hs
		160376 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		AURKA_HUMAN (28-307): 4.39e-43: 160: 32.17
+	Hs
		160446 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		AURKA_HUMAN (28-307): 4.39e-43: 160: 32.17
+	Hs
		160470 PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91		AURKA_HUMAN (28-307): 4.39e-43: 160: 32.17
+	Hs
		160394 PSA5_HUMAN (16-240): 7.6e-75: 228: 16.67		AURKA_HUMAN (28-307): 4.39e-43: 160: 32.17
+	Hs
		160395 PSB5_HUMAN (9-230): 4.76e-73: 224: 20.27		AURKA_HUMAN (28-307): 4.39e-43: 160: 32.17