HitPredict

Interactor 1: PSB1 (P20618)
Proteasome subunit beta type-1 (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain)
Gene: PSMB1

Interactor 2: Q6IBT1 (Q6IBT1)
Proteasome subunit beta
Gene: PSMB7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	25416956
Identification Methods	mammalian protein protein interaction trap
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pr_beta_C~Proteasome, Proteasome~Proteasome
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005839 - proteasome core complex GO:0051603 - proteolysis involved in protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 241 Hs			1 277
+	Hs
		594614 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSB7_HUMAN (1-277): 9.24e-102: 299: 99.64
+	Hs
		832010 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		Q6IBT1_HUMAN (1-277): 8.36e-103: 302: 100.00
+	Hs
		832032 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSB7_HUMAN (1-277): 9.24e-102: 299: 99.64
+	Hs
		771441 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSB10_HUMAN (7-276): 6.06e-90: 269: 57.41
+	Dm
		184456 PSB3_DROME (31-241): 1.58e-80: 241: 24.41		O17311_DROME (10-277): 1.33e-87: 263: 64.07
+	Hs
		594455 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSA5_HUMAN (13-241): 1.25e-81: 247: 18.93
+	Hs
		656173 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSA5_HUMAN (13-241): 1.25e-81: 247: 18.93
+	Hs
		594447 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSA1_HUMAN (16-263): 2.87e-78: 239: 17.80
+	Hs
		594453 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSB8_HUMAN (31-243): 1.84e-77: 237: 24.77
+	Hs
		594458 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSB5_HUMAN (42-243): 3e-76: 234: 26.11
+	Hs
		594457 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSB6_HUMAN (38-229): 8.64e-76: 232: 31.09
+	Hs
		637359 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSA1_HUMAN (16-263): 2.87e-78: 239: 17.80
+	Hs
		656046 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSB8_HUMAN (31-243): 1.84e-77: 237: 24.77
+	Hs
		594550 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		Q5JNW7_HUMAN (31-237): 1.47e-74: 229: 22.12
+	Dm
		1178976 PSB3_DROME (31-241): 1.58e-80: 241: 24.41		Q7K148_DROME (5-251): 2.25e-78: 240: 25.40
+	Hs
		656680 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSB5_HUMAN (42-243): 3e-76: 234: 26.11
+	Hs
		656569 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSB6_HUMAN (38-229): 8.64e-76: 232: 31.09
+	Hs
		594454 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSB9_HUMAN (36-227): 3.42e-21: 90.9: 29.74
+	Hs
		656098 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSB9_HUMAN (36-227): 3.42e-21: 90.9: 29.74
+	Dm
		47633 PSB3_DROME (31-241): 1.58e-80: 241: 24.41		A0AQH0_DROME (42-227): 1.59e-22: 94.4: 29.41