HitPredict

Interactor 1: PSB1 (P20618)
Proteasome subunit beta type-1 (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain)
Gene: PSMB1

Interactor 2: RN149 (Q8NC42)
E3 ubiquitin-protein ligase RNF149 (EC 2.3.2.27) (DNA polymerase-transactivated protein 2) (RING finger protein 149) (RING-type E3 ubiquitin transferase RNF149)
Gene: RNF149

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36610398
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 241 Hs			1 400
+	Hs
		156325 PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54		RN149_HUMAN (1-400): 4.22e-129: 378: 100.00
+	Hs
		656744 PSB5_HUMAN (9-230): 4.76e-73: 224: 20.27		RN149_HUMAN (1-400): 4.22e-129: 378: 100.00
+	Hs
		594578 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		GOLI_HUMAN (30-374): 2.45e-84: 264: 40.52
+	Hs
		832016 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		GOLI_HUMAN (30-374): 2.45e-84: 264: 40.52
+	Hs
		156322 PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54		GOLI_HUMAN (30-374): 2.45e-84: 264: 40.52
+	Hs
		893707 PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91		GOLI_HUMAN (30-374): 2.45e-84: 264: 40.52
+	Hs
		638163 PSA4_HUMAN (8-240): 1.49e-75: 231: 17.72		GOLI_HUMAN (30-374): 2.45e-84: 264: 40.52
+	Hs
		656740 PSB5_HUMAN (9-230): 4.76e-73: 224: 20.27		GOLI_HUMAN (30-374): 2.45e-84: 264: 40.52
+	Hs
		594575 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		SYVN1_HUMAN (134-366): 7.61e-39: 148: 18.88
+	Hs
		594657 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		AMFR_HUMAN (96-398): 5.47e-37: 143: 15.29
+	Hs
		832014 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		SYVN1_HUMAN (134-366): 7.61e-39: 148: 18.88
+	Hs
		832055 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		AMFR_HUMAN (96-398): 5.47e-37: 143: 15.29
+	Hs
		156321 PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54		SYVN1_HUMAN (134-366): 7.61e-39: 148: 18.88
+	Hs
		893702 PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91		SYVN1_HUMAN (134-366): 7.61e-39: 148: 18.88
+	Hs
		156372 PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54		AMFR_HUMAN (96-398): 5.47e-37: 143: 15.29
+	Hs
		893769 PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91		AMFR_HUMAN (96-398): 5.47e-37: 143: 15.29
+	Hs
		656265 PSA5_HUMAN (16-240): 7.6e-75: 228: 16.67		SYVN1_HUMAN (134-366): 7.61e-39: 148: 18.88
+	Hs
		638214 PSA4_HUMAN (8-240): 1.49e-75: 231: 17.72		AMFR_HUMAN (96-398): 5.47e-37: 143: 15.29
+	Hs
		656739 PSB5_HUMAN (9-230): 4.76e-73: 224: 20.27		SYVN1_HUMAN (134-366): 7.61e-39: 148: 18.88
+	Hs
		656334 PSA5_HUMAN (16-240): 7.6e-75: 228: 16.67		AMFR_HUMAN (96-398): 5.47e-37: 143: 15.29