HitPredict

Interactor 1: PSB1 (P20618)
Proteasome subunit beta type-1 (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain)
Gene: PSMB1

Interactor 2: DDI1 (Q8WTU0)
Protein DDI1 homolog 1 (EC 3.4.23.-)
Gene: DDI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.596

Property	Details
Experiments	32296183, 27114451, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 241 Hs			1 396
+	Hs
		832025 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		DDI1_HUMAN (1-396): 4.1e-163: 465: 100.00
+	Hs
		156329 PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54		DDI1_HUMAN (1-396): 4.1e-163: 465: 100.00
+	Hs
		893715 PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91		DDI1_HUMAN (1-396): 4.1e-163: 465: 100.00
+	Hs
		594557 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		DDI2_HUMAN (1-392): 2.76e-155: 445: 70.93
+	Hs
		832005 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		DDI2_HUMAN (1-392): 2.76e-155: 445: 70.93
+	Hs
		156308 PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54		DDI2_HUMAN (1-392): 2.76e-155: 445: 70.93
+	Hs
		893686 PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91		DDI2_HUMAN (1-392): 2.76e-155: 445: 70.93
+	Hs
		594660 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		UBQL1_HUMAN (5-249): 3.83e-47: 171: 14.74
+	Hs
		594653 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		UBQL2_HUMAN (5-249): 4.55e-46: 168: 14.74
+	Hs
		832058 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		UBQL1_HUMAN (5-249): 3.83e-47: 171: 14.74
+	Hs
		832053 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		UBQL2_HUMAN (5-249): 4.55e-46: 168: 14.74
+	Hs
		594643 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		UBQL4_HUMAN (8-249): 3.58e-43: 160: 14.24
+	Hs
		156375 PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54		UBQL1_HUMAN (5-249): 3.83e-47: 171: 14.74
+	Hs
		156369 PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54		UBQL2_HUMAN (5-249): 4.55e-46: 168: 14.74
+	Hs
		832046 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		UBQL4_HUMAN (8-249): 3.58e-43: 160: 14.24
+	Hs
		156361 PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54		UBQL4_HUMAN (8-249): 3.58e-43: 160: 14.24
+	Dm
		1375076 PSB3_DROME (31-241): 1.58e-80: 241: 24.41		Q9VWD9_DROME (5-249): 3.39e-41: 154: 13.55
+	Hs
		594505 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		RS27A_HUMAN (5-93): 5.56e-24: 98.8: 17.98
+	Hs
		831974 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		RS27A_HUMAN (5-93): 5.56e-24: 98.8: 17.98
+	Hs
		893645 PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91		RS27A_HUMAN (5-93): 5.56e-24: 98.8: 17.98