HitPredict

Interactor 1: PSB1 (P20618)
Proteasome subunit beta type-1 (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain)
Gene: PSMB1

Interactor 2: PSMF1 (Q92530)
Proteasome inhibitor PI31 subunit (hPI31)
Gene: PSMF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	33961781, 35271311, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005839 - proteasome core complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 241 Hs			1 271
+	Hs
		832026 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		156330 PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		893716 PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		638170 PSA4_HUMAN (8-240): 1.49e-75: 231: 17.72		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		656281 PSA5_HUMAN (16-240): 7.6e-75: 228: 16.67		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00
+	Hs
		893684 PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91		Q5QPM9_HUMAN (1-183): 1.97e-104: 302: 100.00
+	Dm
		1360134 PSA6_DROME (19-240): 1.71e-66: 207: 15.04		PSMF1_DROME (3-270): 5e-108: 315: 29.46
+	Hs
		832146 PSB2_HUMAN (40-233): 2.78e-09: 57: 24.62		PSMF1_HUMAN (1-271): 3.2e-157: 439: 100.00