HitPredict

Interactor 1: PSB1 (P20618)
Proteasome subunit beta type-1 (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain)
Gene: PSMB1

Interactor 2: POMP (Q9Y244)
Proteasome maturation protein (Proteassemblin) (Protein UMP1 homolog) (hUMP1) (Voltage-gated K channel beta subunit 4.1)
Gene: POMP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.953

Property	Details
Experiments	28514442, 33961781, 35271311, 14733938, 17506986, 17948026
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Proteasome~UMP1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 241 Hs			1 141
+	Hs
		832060 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		156378 PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		656085 PSB8_HUMAN (14-230): 1.02e-77: 237: 21.27		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		893773 PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		638220 PSA4_HUMAN (8-240): 1.49e-75: 231: 17.72		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		656342 PSA5_HUMAN (16-240): 7.6e-75: 228: 16.67		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		656796 PSB5_HUMAN (9-230): 4.76e-73: 224: 20.27		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Hs
		656662 PSB6_HUMAN (34-236): 8.15e-56: 180: 21.68		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00
+	Dm
		1367997 PSB3_DROME (31-241): 1.58e-80: 241: 24.41		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1278643 PSA5_DROME (16-240): 5.24e-75: 229: 17.37		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1178961 Q7K148_DROME (19-230): 2.86e-69: 215: 18.43		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		771419 PSB1_DROME (30-241): 2.46e-68: 212: 52.34		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		1367998 PSA6_DROME (19-240): 1.71e-66: 207: 15.04		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Dm
		47622 A0AQH0_DROME (34-235): 9.99e-64: 199: 26.24		Q9VIJ5_DROME (40-140): 1.87e-46: 148: 50.50
+	Hs
		832181 PSB2_HUMAN (40-233): 2.78e-09: 57: 24.62		POMP_HUMAN (1-141): 3.89e-75: 221: 100.00