HitPredict

Interactor 1: PSB1 (P20618)
Proteasome subunit beta type-1 (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain)
Gene: PSMB1

Interactor 2: FBX7 (Q9Y3I1)
F-box only protein 7
Gene: FBXO7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	27497298, 27503909, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 241 Hs			1 522
+	Hs
		832063 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		156380 PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		893775 PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		638222 PSA4_HUMAN (8-240): 1.49e-75: 231: 17.72		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		656346 PSA5_HUMAN (16-240): 7.6e-75: 228: 16.67		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		656798 PSB5_HUMAN (9-230): 4.76e-73: 224: 20.27		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		656663 PSB6_HUMAN (34-236): 8.15e-56: 180: 21.68		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		832184 PSB2_HUMAN (40-233): 2.78e-09: 57: 24.62		FBX7_HUMAN (1-522): 0: 1102: 100.00