Interactor 1: TRX (P20659)
Histone-lysine N-methyltransferase trithorax (EC 2.1.1.355) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Lysine N-methyltransferase 2A)
Gene: TRX

Interactor 2: ASH1 (Q9VW15)
Histone-lysine N-methyltransferase ash1 (EC 2.1.1.354) (Absent small and homeotic disks protein 1) (Lysine N-methyltransferase 2H)
Gene: ASH1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.775

The method score is based on:

Property Details
Experiments 10454589, unassigned4
Identification Methods affinity chromatography technology, two hybrid, experimental interaction detection
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains BAH~PHD, AWS~SET, SET~SET
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005700 - polytene chromosome
GO:0032259 - methylation
GO:0035097 - histone methyltransferase complex
and 1 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 3726
Dm

1 2226
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+ Dm
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+ Mm
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Last updated: 15 Jul 2024